generic · 12th TN - English Medium · BIO ZOOLOGY · Page 67

5.2 In search of the genetic material

Chapter 5: CHAPTER 5 · BIO ZOOLOGY · EN medium

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As early as , Wilhelm Hofmeister, a German botanist, had observed that cell nuclei organize themselves into small, rod like bodies during mitosis called chromosomes . In , Friedrich Miescher, a Swiss physician, isolated a substance from the cell nuclei and called it as nuclein . It was renamed as nucleic acid by Altman ( ), and is now known as DNA. By , it became clear that chromosomes are made up of proteins and DNA. Many experiments were carried out to study the actual carriers of genetic information. Griffith's experiment proved that DNA is the genetic material which has been dealt in class XI. Bacterial transformation experiments provided the first proof that DNA is the genetic material.

📖 Class 12 Bio Zoology English 2024 Edition www.tntextbooks.in · Page 67

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As early as , Wilhelm Hofmeister, a German botanist, had observed that cell nuclei organize themselves into small, rod like bodies during mitosis called chromosomes . In , Friedrich Miescher, a Swiss physician, isolated a substance from the cell nuclei and called it as nuclein . It was renamed as nucleic acid by Altman ( ), and is now known as DNA. By , it became clear that chromosomes are made up of proteins and DNA.

Many experiments were carried out to study the actual carriers of genetic information. Griffith's experiment proved that DNA is the genetic material which has been dealt in class XI. Bacterial transformation experiments provided the first proof that DNA is the genetic material. However, he could not understand the cause of bacterial transformation, and the biochemical nature of genetic material was not defined from his experiments.

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