COMMENTS

COMMENTS . Karyotyping is a technique through which a complete set of chromosomes are separated from a cell and are arranged in pairs. . A diagrammatic representation of chromosomes is called an idiogram. . There are pairs of autosomes and a pair of allosomes ( XX- female, XY – male) arranged based on their size, shape, banding pattern and position of centromere. . It helps in gender identification and to detect genetic diseases. A B C D F E G x y Human pancreas cell DNA Human insulin Recombinant Bacterium Human insulin-producing gene Introduction of recombinant DNA into a bacterial cell Fermentation Tank Recombinant DNA Plasmid DNA Bacterial DNA Bacterium Plasmid DNA cut with restriction enzymes Human insulin B chain Insulin COOH H N H N COOH A chain S S S S S S B chain A chain C chain COOH H N Pre pro insulin Signal peptide B chain Pro insulin C chain A chain H N COOH S S S S Extraction & purification of human insulin Recombinant bacteria multiplying and producing human insulin in fermentation tank XII Std Biology-Zoology Practical XII Std Biology-Zoology Practical . AUTOSOMAL ANOMALY – PATAU’S SYNDROME