generic · 12th TN - English Medium · ZOOLOGY · Page 59

1. Haemophilia

Chapter 1: Chapter 1 · ZOOLOGY · EN medium

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Haemophilia is commonly known as bleeder’s disease, which is more common in men than women. This hereditary disease was first reported by John Cotto in . Haemophilia is caused by a recessive X-linked gene. A person with a recessive gene for haemophilia lacks a normal clotting substance (thromboplastin) in blood, hence minor injuries cause continuous bleeding, leading to death. The females are carriers of the disease and would transmit the disease to % of their sons even if the male parent is normal. Haemophilia follows the characteristic criss - cross pattern of inheritance.

📖 Class 12 Zoology English 2024 Edition www.tntextbooks.in · Page 59

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Haemophilia is commonly known as bleeder’s disease, which is more common in men than women. This hereditary disease was first reported by John Cotto in . Haemophilia is caused by a recessive X-linked gene. A person with a recessive gene for haemophilia lacks a normal clotting substance (thromboplastin) in blood, hence minor injuries cause continuous bleeding, leading to death.

The females are carriers of the disease and would transmit the disease to % of their sons even if the male parent is normal. Haemophilia follows the characteristic criss - cross pattern of inheritance.

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