beings

beings Mitotic or meiotic non-disjunction of sex chromosomes causes allosomal abnormalities. Several sex chromosomal abnormalities have been detected. Eg. Klinefelter’s syndrome and Turner’s syndrome. . Klinefelter’s Syndrome (XXY Males) This genetic disorder is due to the presence of an additional copy of the X chromosome resulting in a karyotype of ,XXY. Persons with this syndrome have chromosomes (44AA+XXY). They are usually sterile males, tall, obese, with long limbs, high pitched voice, under developed genitalia and have feeble breast (gynaecomastia) development. . Turner’s Syndrome (XO Females) This genetic disorder is due to the loss of a X chromosome resulting in a karyotype of ,X. Persons with this syndrome have chromosomes ( autosomes and one X chromosome) (44AA+XO) and are sterile females. Low stature, webbed neck, under developed breast, rudimentary gonads lack of menstrual cycle during puberty, are the main symptoms of this syndrome.